SIMDIVGenerate data sets under an isolation with migration model | |
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SIMDIV Description
SIMDIV was developed to be a program that can be used in the Hey lab for generating data sets under an isolation with migration model. It can be used for multiple populations for a variety of mutation models – pretty much for any kind of data set for which IM and related programs can be used. SIMDIV is not the only program that can do this. There are lots of other coalescent simulators out there, and one that I know can be used for isolation with migration models is SIMCOAL, but there may be others. SIMDIV will simulate data with recombination if the users so specifies, even though IM programs assume no recombination. The program can handle up to 10 populations, with 350 gene copies per locus, for any number of loci. If desired a user can load all of the specifics associated with a real data set (# loci, sample sizes, mutation models, and IM parameter estimates) so that IM/SIMDIV results can be compared with the real data that was used to generate the parameter estimates. For IM users SIMDIV should be fairly easy to use because parameters mean the same things and are scaled the same way in SIMDIV and the IM programs.
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