PHIRE

Searches on bacteriophage genome sequences for blocks that display sequence similarity.
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PHIRE Ranking & Summary

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  • Rating:
  • License:
  • Freeware
  • Publisher Name:
  • Katholieke Universiteit Leuven
  • Operating Systems:
  • Windows All
  • File Size:
  • 4.2 MB

PHIRE Tags


PHIRE Description

The PHIRE program, a standalone program in Visual Basic, performs an algorithmic string-based search on bacteriophage genome sequences, discovering and extracting blocks displaying sequence similarity, corresponding to conserved regulatory elements contained within these genomes in a systematic manner, without any prior experimental or predictive knowledge. PHIRE systematically compares all the DNA substrings of a specified length (L) to one another, allowing a limited number of mismatches (degeneracy D) to sort out and extract the largest sets (DominantNum) of substrings that represent a unique consensus. This way, the entire genome will be analysed on the Watson and crick DNA strand as well. In order to visualize the sequences around the consensus sequence, the window size (W) can be adapted to include the sequences left and right of each selected DNA individual string.


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