ICPLQuant free download, ICPLQuant download on software download

ICPLQuant is a new software suite specially developed to accurately quantify ICPL-labeled peptides on the MS level during LC-MALDI and peptide mass fingerprint experiments. One big bottleneck in quantitative proteomics remains the availability for powerful software to evaluate the raw data automatically. In case of the ICPL Quadruplex technology it is necessary to detect the quadruplets (ICPL0, ICPL4, ICPL6 and ICPL10 label) in MS mode. The second step is the determination of the ratios of the four quadruplet peptides. In a third step at least one of the four peptides in each quadruplet has to be selected for MS/MS for sequence identification. Main features: Quantification of all multiplets correcting for isotopic impurities of reagents. Preparation of a precursor list containing peptides with user defined regulation factors for MS/MS analysis. MASCOT .dat file parser Merging of quantification information and identification information Protein and peptide output lists in open formats, easily accessible for data mining programs Visual display of LC profiles Computation of protein quantitation ratios (with standard deviation estimation) Export of results to files, Excel and to databases Further support in progress: vendor Thermo Electron/Finnigan; Orbitrap; software package XCalibur (.raw file)