SflashKiller for Mac Kill Flash in Safari with one click.
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SflashKiller for Mac Description

SflashKiller is a simple app to kill the Flash Player process for Safari with one click of the mouse. Drag SflashKiller into the dock and whenever Safari becomes unresponsive because of Flash, all you have to do is to click the SflashKiller icon to free all the memory and CPU consumption that was used up by Flash, and happily resume your browsing. Only the Flash Player is killed: none of your Safari tabs are closed. This little app only works with Safari 5 and up. (It will probably work with Safari 4, but that was not tested.)

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