Mauve Constructs global multiple alignments of rearranged genome sequences
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construct alignment construct alignment genome sequence rearanged genome rearange

Mauve Description

Constructs global multiple alignments of rearranged genome sequences Mauve is a system for efficiently constructing multiple genome alignments in the presence of large-scale evolutionary events such as rearrangement and inversion. Multiple genome alignment provides a basis for research into comparative genomics and the study of evolutionary dynamics on a new scale. Aligning whole genomes is a fundamentally different problem than aligning short sequences.Mauve has been developed with the idea that a multiple genome aligner should require only modest computational resources. Mauve employs algorithmic techniques that scale well in the amount of sequence being aligned.For example, a pair of Y. pestis genomes can be aligned in under a minute, while a group of 9 divergent Enterobacterial genomes can be aligned in a few hours. What's New in This Release: New features: · Compatibility with older versions of Mac OS X Bugs fixed: · SNP output now handles mixed case sequence files and gap characters · Aligner memory usage has been streamlined, resulting in reduced memory requirements for alignments with many genomes · Fix for bug that prevented reordering GenBank-format draft genomes on the command-line · Fixed a crash when generating mums · Report an error when sequences containing gaps are used as input · Remove extra newlines in the ortholog alignment output · Fixed an OpenJDK rectangle drawing bug

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