CLC Main Workbench

Bioinformatics program for advanced protein and DNA sequence analysis.
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CLC Main Workbench Ranking & Summary

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  • Rating:
  • License:
  • Trial
  • Price:
  • N/A | BUY the full version
  • Publisher Name:
  • CLC bio
  • Publisher web site:
  • http://www.clcbio.com
  • Operating Systems:
  • Mac OS X 10.3 or later
  • File Size:
  • 49.4 MB

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CLC Main Workbench Description

Bioinformatics program for advanced protein and DNA sequence analysis. This 2 x 2 weeks of fully functional demo of CLC Main Workbench aggregates all DNA sequence analyses of CLC Gene Workbench and all protein sequence analyses of CLC Protein Workbench.CLC Main Workbench is a tool that integrates all analyzes in one single, user-friendly, and intuitive software application. Here are some key features of "CLC Main Workbench": · Assembly of DNA sequencing data. · Advanced primer design. · Molecular cloning. · Automatic SNP annotation of sequences. · Secondary protein structure prediction. · Integrated 3D molecular view. · Signal Peptide Prediction (SignalP). · Transmembrane helix prediction (TMHMM). · Protein family analysis (PFAM). · 2 types of alignments. · Phylogenetics. · Motif search (known patterns). · Pattern discovery (unknown patterns). · BLAST. · Batch processing of multiple analyses in one work-step. · Dot plots. · Hydrophobicity analyses. · Antigenicity analyses. · Searches on GenBank, SwissProt, TrEMBL, and PubMed. · Detailed log of actions/analyses performed. Requirements: · 256 MB RAM required. · 512 MB RAM recommended. · 1024 x 768 display recommended. Limitations: · 4 weeks fully functional trial period. What's New in This Release: Expression analysis: · Volcano plots: you can now choose the values to plot on the x-axis. Choose between "Difference" and "Fold change". Read more... · Table view of bar plots shows the same intervals as are shown in the bar plot. · Generic importer for expression array data in tabular format. Read more... · Generic importer for expression experiment annotation data in tabular format. Read more... · Gene Ontology (GO) files can now be used to annotate an expression experiment. Read more... · Tag profiling: You are no longer allowed to annotate tag samples, only experiments · Side panel of experiment table has been re-organized to provide better overview. Read more... · Opening consensus sequence including gaps will also put Ns before the consensus sequence starts and after it ends Deployment: · You can set a path to the default data location used when the Workbench starts for the first time. This is a feature to help system administrators control where new installations per default save their data. Read more... · Support for removing tools accessing the internet (NCBI BLAST, update notifications etc). Read more... General import and export: · Support for import of complex regions from GFF files · Export tables and reports in Excel format. · Import section of user manual re-structured to provide better overview. Read more.... Expression data importers are now described in technical details in a separate section. Read more.... · You can now export multiple sequence lists in fasta format · Forced import of zip files is now supported (it will force import the contents of the zip file) · The standard import now accepts gzip and tar files as well as zip · If a forced import fails, there will be more technical information about what went wrong, allowing you to identify bad formatting of the import files · Both Genbank and gff importer now makes several attempts at naming genes that do not have a gene name. It will iteratively try the following qualifiers: "product", "locus_tag", "protein_id" and "transcript_id" · When importing genbank files where the length stated does not match the actual sequence, a warning is shown but the sequence is accepted. · When exporting in csv format, the Locale settings are used to determine whether comma or semi-colons should be used as delimiter (comma used for US locales) · GFF plug-in has been updated to accept complex annotations Miscellaneous: · Advanced retyping of annotations using the annotation table. Read more... · Improved reporting of situations when a full disk prevents saving of data · Downloading sequences using drag and drop from the search table no longer creates a "Downloading..." node in the folder. The download process can be monitored in the Processes tab. · Primer design now supports PCR fragments longer than 5000 bp. · Extract Sequences moved from File manu to Toolbox-> General Sequence Analysis. Read more... · Better progress feedback on various dialogs Bug-fixes: · Fixed problem displaying the "Copying..." label when copying data and then updating the folder · Fixed problem with naming of tabs. The fix means that on Windows and Linux unsaved data now gets a * rather than make the tab name bold and italics. (This has always been the behavior on Mac OS X).


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