SigInt SigInt project is a command-line software tool that can be used to find and rank mammalian proteins/genes.
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SigInt Description

SigInt project is a command-line software tool that can be used to find and rank mammalian proteins/genes. SigInt project is a command-line software tool that can be used to find and rank mammalian proteins/genes that specifically and significantly interact with a list of proteins/genes in context of a background mammalian signalome and interactome networks.The inputs to the program are: (a) a seed list of human Entrez Gene gene symbols, (b) a background networks in SIG format, and (c) a name for the output file (web-page file name with the htm extension). SigInt outputs a sorted list of genes/proteins that interacts with components from the seed list. These components are sorted by a z-score that measures the specificity of these intermediate components to interact with the genes/proteins from the seed list.SigInt can be run on Linux, Mac and Windows operating systems and it requires a background network text file in SIG format.Usage:Extract the archivechmod +x sigint_lnx.exe./sigint_lnx.exe

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