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File Size: 341 KB
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License: Freeware
Price: $0.00
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Publisher: Mount Sinai School of Medicine Iyengar Lab
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SigInt Description

SigInt is a command-line software utility that can be used to find and rank mammalian proteins/genes that specifically and significantly interact with a list of proteins/genes in context of a background mammalian signalome and interactome networks.
The inputs to the program are:
· a seed list of human Entrez Gene gene symbols,
· a background networks in SIG format, and
· a name for the output file (web-page file name with the htm extension)
SigInt outputs a sorted list of genes/proteins that interacts with components from the seed list. These components are sorted by a z-score that measures the specificity of these intermediate components to interact with the genes/proteins from the seed list.

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Mount Sinai School of Medicine Iyengar Lab

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